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Table 1 NADH:quinone oxidoreductase activity in control and transfected cells

From: Arabidopsis thaliana alternative dehydrogenases: a potential therapy for mitochondrial complex I deficiency? Perspectives and pitfalls

Cell line NADH:quinone oxidoreductase specific activity w/o rotenone (nmol/min/mg Prot) NADH:quinone oxidoreductase specific activity with rotenone (nmol/min/mg Prot) Inhibition (%)
NHDF 7.7 (±0.5) 1.7 (±0.2) 78.3%
79,787 2.5 (±0.2) 1.4 (±0.1) 42.6%
79,787-T-ScNDI1 24.0 (±8.7) 20.7 (±8.3) 13.7%
79,787-T-AtNDB4 11.8 (±2.4) 10.6 (±1.9) 10.0%
79,787-T-ATNDA2 5.3 (±0.9) 5.3 (±0.9) 2.7%
  1. Spectrophotometric assessment of NADH:quinone oxidoreductase specific activity in control cells (NDHF) and NDUFS4 cell line untransfected (79787) and transfected with alternative NADH oxidases (ScNDI1, AtNDA2 and AtNDB4). Values are expressed as mean ± SD