Table 1 NADH:quinone oxidoreductase activity in control and transfected cells
Cell line | NADH:quinone oxidoreductase specific activity w/o rotenone (nmol/min/mg Prot) | NADH:quinone oxidoreductase specific activity with rotenone (nmol/min/mg Prot) | Inhibition (%) |
|---|---|---|---|
NHDF | 7.7 (±0.5) | 1.7 (±0.2) | 78.3% |
79,787 | 2.5 (±0.2) | 1.4 (±0.1) | 42.6% |
79,787-T-ScNDI1 | 24.0 (±8.7) | 20.7 (±8.3) | 13.7% |
79,787-T-AtNDB4 | 11.8 (±2.4) | 10.6 (±1.9) | 10.0% |
79,787-T-ATNDA2 | 5.3 (±0.9) | 5.3 (±0.9) | 2.7% |