Fig. 3
From: Novel mutations and the ophthalmologic characters in Chinese patients with Wolfram Syndrome
Optic coherence tomography (OCT) of the patient with CISD2 mutation. OCT shows peripapillary retinal nerve fiber layer (RNFL) and ganglion cell lay complex (GCC) thickness significantly decreasing. The upper graphs show the thickness pattern of GCC (left) and RNFL (right) in the right eye, and the lower graphs for the left eye respectively. The red part represents the decreasing of the thickness less than 1% outside normal, and the green part indicate within the normal limit. The number labels around the optic nerve head map indicating the thickness of RNFL (μm). GCC: ganglion cell lay complex; RNFL: retinal nerve fiber layer; T: temporal; N: nasal; S: superior; I: inferior