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Table 2 Updated CCI categories among the PKU cohort and the matched cohort

From: Clinical burden of illness in patients with phenylketonuria (PKU) and associated comorbidities - a retrospective study of German health insurance claims data

  PKU patients (n = 377) Control group (n = 3,770) Chi2 test p value PR (95% CI)
n % n %
CCI = 0 194 51.5 2,206 58.5 0.001 0.9 (0.79–0.97)
CCI = 1 72 19.1 716 19.0 1.000 1.0 (0.81–1.25)
CCI = 2 35 9.3 353 9.4 1.000 1.0 (0.71–1.38)
CCI = 3 30 8.0 189 5.0 0.021 1.6 (1.10–2.30)
CCI ≥ 4 46 12.2 306 8.1 0.009 1.5 (1.12–2.01)
  1. CCI of 0 = no comorbidities, ≥4 = severe comorbidities