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Table 8 Guidance statements for hip replacement, hip reconstruction and growth modulation surgery

From: Recommendations for the management of MPS VI: systematic evidence- and consensus-based guidance

Statement Percentage consensus
Hip replacement can be considered in adult patients with MPS VI who exhibit hip pain, reduced walking and endurance related to hip disease, as well as abnormal radiographic findings
Evidence Grade: D (limited published evidence)
100%
Hip reconstruction is not routinely indicated, but may be considered in paediatric patients with MPS VI who exhibit hip pain, reduced walking and endurance related to hip disease, as well as abnormal radiographic findings
Evidence Grade: D (limited published evidence)
92%
Growth modulation surgery is recommended in patients with MPS VI who have signs of genu valgum and should be performed as early as possible during the period of growth
Evidence Grade: D (limited published evidence)
87%