Table 5 Literature review on SDS-PAGE results of RBC membrane protein abnormalities in patients with HS (%)
RBC membrane protein | Italy2[16] (n = 87) | Italy1[9] (n = 300) | USA2[6] (n = 55) | USA1[29] (n = 166) | Spain[30] (n = 62) | Japan2*[31] (n = 60) | Japan1[32] (n = 47) | Korea[28] (n = 27) |
|---|---|---|---|---|---|---|---|---|
Band 3 | 23 (26) | 158 (53) | 10 (18) | 38 (23) | 0 | (20) | 15 (32) | 3 (11) |
Spectrin only | 36 (41) | 98 (33) | 7 (13) | 0 | 19 (31) | 0 | 8 (15) | 2 (7) |
Ankyrin only | 0 | 13 (4)†| 0 | 0 | 4(6) | (7) | 1 (2) | 8 (30) |
Spectrin/ankyrin | 16 (18) | 6 (11) | 100 (60) | 34 (55) | 0 | 1 (2) | 1 (4) | |
Other combination | – | – | – | – | – | – | 15 (34) | – |
4.2 protein | 6 (7) | 2 (1) | 0 | 3 (2) | 0 | (45) | 3 (6) | 4 (15) |
Undetected | 6 (7) | 29 (10) | 32 (58) | 25 (15) | 5 (8) | (28) | 4 (9) | 9 (33) |