Table 5 Incidence of adverse events with onset 4 weeks after randomization by received treatment
Enalapril and Metoprolol | Placebo | Difference between groups | ||||
|---|---|---|---|---|---|---|
Preferred term | No. | (%) | No. | (%) | (%) | 95% confidence intervals |
Total number of patients | 21 | (100%) | 16 | (100%) | ||
Patients with at least one AE | 21 | (100%) | 15 | (94%) | 6% | (−10 to 28%) |
Febrile infection | 11 | (52%) | 5 | (31%) | 21% | (−10 to 47%) |
Nasopharyngitis | 10 | (48%) | 5 | (31%) | 16% | (−15 to 43%) |
Diarrhoea | 6 | (29%) | 1 | (6%) | 22% | (−4 to 44%) |
Cough | 4 | (19%) | 5 | (31%) | −12% | (−39 to 15%) |
Headache | 4 | (19%) | 5 | (31%) | −12% | (− 39 to 15%) |
Mechanical ventilation | 3 | (14%) | 1 | (6%) | 8% | (−16 to 29%) |
Abdominal pain upper | 3 | (14%) | 0 | 14% | (−7 to 35%) | |
Gastroenteritis | 3 | (14%) | 0 | 14% | (−7 to 35%) | |
Spinal operation | 2 | (10%) | 3 | (19%) | −9% | (−34 to 14%) |
Immunisation | 2 | (10%) | 2 | (13%) | −3% | (−27 to 18%) |
Pyrexia | 2 | (10%) | 2 | (13%) | −3% | (−27 to 18%) |
Lower limb fracture | 2 | (10%) | 1 | (6%) | 3% | (−20 to 23%) |
Oropharyngeal pain | 2 | (10%) | 1 | (6%) | 3% | (−20 to 23%) |
Chest pain | 2 | (10%) | 0 | 10% | (−11 to 29%) | |
Fatigue | 2 | (10%) | 0 | 10% | (−11 to 29%) | |
Humerus fracture | 2 | (10%) | 0 | 10% | (−11 to 29%) | |
Influenza like illness | 2 | (10%) | 0 | 10% | (−11 to 29%) | |
Photosensitivity reaction | 2 | (10%) | 0 | 10% | (− 11 to 29%) | |
Tonsillitis | 2 | (10%) | 0 | 10% | (−11 to 29%) | |
Upper respiratory tract infection | 2 | (10%) | 0 | 10% | (−11 to 29%) | |