Gene | Genotype | Genotype distribution | MAIP frequency | ||||
---|---|---|---|---|---|---|---|
N | % | % | OR | CI 95% | P value | ||
CYP2C9 | two normal alleles | 27 | 54 | 55.6 | 0.45 | 0.17–1.09 | 0.092 |
one allele *2 or *3 | 17 | 34 | 58.8 | ||||
two alleles *2 or *3 | 6 | 12 | 16.7 | ||||
CYP2C19 | two normal alleles | 35 | 70 | 48.6 | 1.75 | 0.49–6.81 | 0.398 |
one allele *2 | 15 | 30 | 60.0 | ||||
two alleles *2 | 0 | 0 | – | ||||
CYP2D6 | two normal alleles | 38 | 76 | 60.5 | 0.2 | 0.04–0.81 | 0.037 |
one allele *4 or *5 | 11 | 22 | 27.3 | ||||
two alleles *4 or *5 | 1 | 2 | 0 | ||||
CYP3A4 | two normal alleles | 47 | 94 | 51.1 | 1.94 | 0.14–49.63 | 0.629 |
one allele *1B | 3 | 6 | 66.7 | ||||
two alleles *1B | 0 | 0 | – | ||||
CYP3A5 | two normal alleles | 0 | 0 | – | 0.67 | 0.07–5.02 | 0.697 |
one allele *3 | 5 | 10 | 60.0 | ||||
two alleles *3 | 45 | 90 | 51.1 |