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Table 2 CYP allelic frequencies

From: High penetrance of acute intermittent porphyria in a Spanish founder mutation population and CYP2D6 genotype as a susceptibility factor

Gene

Allele

Total AIP

LAIP

MAIP

P value

CYP2C9

*2

0.28

0.33

0.23

0.255

*3

0.01

0.02

0

CYP2C19

*2

0.15

0.13

0.17

0.695

CYP2D6

*4

0.12

0.19

0.06

0.052

*5

0.01

0.02

0

CYP3A4

*1B

0.03

0.02

0.04

1.000

CYP3A5

*3

0.95

0.96

0.94

0.913

  1. MAIP manifest AIP, LAIP latent AIP