From: High penetrance of acute intermittent porphyria in a Spanish founder mutation population and CYP2D6 genotype as a susceptibility factor
Gene
Allele
Total AIP
LAIP
MAIP
P value
CYP2C9
*2
0.28
0.33
0.23
0.255
*3
0.01
0.02
0
CYP2C19
0.15
0.13
0.17
0.695
CYP2D6
*4
0.12
0.19
0.06
0.052
*5
CYP3A4
*1B
0.03
0.04
1.000
CYP3A5
0.95
0.96
0.94
0.913