Fig. 7From: FGF23 and its role in X-linked hypophosphatemia-related morbidityFGF23 and cranial abnormalities. Over-expression of FGF23 leads to up-regulation of FGFR2/3 signalling. Cross-binding of FGF23 with FGFR2/3 at cranial sutures, impaired endochondral ossification of the skull, and osteomalacia-induced malformation of the base plate can all lead to craniosynostosisBack to article page