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Table 5 Changes in the median (range) blood Phe concentrations (μmol/L) within and between the CGMP-AA2 and Phe-free L-AA group at baseline, 26 and 52 weeks for children < 12 years

From: Glycomacropeptide: long-term use and impact on blood phenylalanine, growth and nutritional status in children with PKU

Group

Number of subjects

Baseline μmol/L (range)

Wk 26 μmol/L (range)

Wk 52 μmol/L (range)

P value

CGMP-AA2

25

270 §* (170–360)

300§ (125–415)

290* (200–450)

§p = 0.04 *p = 0.04

Phe-free L-AA

9

288 §§** (140–470)

287§§ (180–348)

291* (190–344)

§P = 0.90 **p = 0.41

  1. Wilcoxon test § GMP baseline to 26 wk., * GMP baseline to 52 wk
  2. Wilcoxon test §§ L-AA baseline to 26 wk., ** L-AA baseline to 52 wk
  3. ABABBREVIATIONS: CGMP-AA low phenylalanine glycomacropeptide protein substitute supplemented with L-amino acids, Phe-free L-AA Phenylalanine free L-amino acid supplement
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172