Fig. 3
From: Disease progression in women with X-linked adrenoleukodystrophy is slow
Volcano plot and biomarker ratios. a Volcano plot of lipid levels normalized to the corresponding internal standard. The vertical axis contains the p-value (−log10) from t tests between women with ALD and controls, and the horizontal axis the fold change (log2) between women with ALD and controls. Red and blue coloured dots are lipids with a p value < 0.001 and an absolute fold change (log2) larger than one, which were considered potentially interesting biomarkers. b A representative sample of the top 100 biomarker ratios with strong differentiating properties and non-overlapping data distributions between women with ALD and healthy control females. Cer = ceramide; LPA = lysophosphatidic acid; LPE = lysophosphatidylethanolamine; LPC = lysophosphatidylcholine; PC = phosphatidylcholine; PS = phosphatidyloserine; SM = sphingomyelin