Fig. 1
From: Tracking sex-dependent differences in a mouse model of CLN6-Batten disease
Sex differences evident in Cln6nclf accumulation of autofluorescent storage material (ASM) and mitochondrial ATP synthase subunit C in brain. a Male Cln6nclf mice show enhanced ASM in the somatosensory cortex at two months of age, while female Cln6nclf mice overtake their male counterparts at six months of age in the VPM/VPL and somatosensory cortex. b Female mice show enhanced subunit C expression at two months of age, that corrects as the animals age to six month. Images represent the six month time point only. N = 3–5, ***p < 0.001, ****p < 0.0001