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Table 7 Main AEs’ rates (for grades 1–5) in present series compared to literature data on BZB and TH in oncology (or other) settings

From: Safety of thalidomide and bevacizumab in patients with hereditary hemorrhagic telangiectasia

 

Present study %

Literature [64,65,66,67,68,69,70,71,72] %

Bevacizumab

 Hypertension

7.2

5–19

 Bleeding

2.8

1.7–6.7

 Proteinuria

2.8

0.7–7.4

 Arterial thromboembolism

1.4

0.7–4.4

 Peripheral neuropathy

Not described

6.3

Thalidomide

 Somnolence/drowsiness

16

2–23

 Peripheral neuropathy

17.9

1–44

 Thromboembolic event

2.9

1–6

 Cardiac failure

1.4

1–8

 Bleeding

1.4

Not described