Start of exposure period

Model 1

Model 2

Model 3


First symptoms of LAM

0.12 (0.1, 0.14)

0.18 (0.13, 0.24)

0.08 (0.05, 0.11)

LAM diagnosis
 
0.09 (0.07, 0.11)

0.11 (0.07, 0.15)

0.05 (0.03, 0.08)

 Data were calculated from 3 models: Model 1: constant risk of PT across the whole LAM population, standard Poisson regression. Model 2: variable risk from one patient to another, negative binomial regression. Model 3: variable risk from one patient to another, Poisson regression with random intercept. Results are expressed as incidence per patient per year (95% confidence intervals)