Skip to main content

Table 6 Association between diagnostic delay and the prevalence of comorbidities in the CVID cohort. Results of proportional Cox regression (N = 972)

From: The burden of common variable immunodeficiency disorders: a retrospective analysis of the European Society for Immunodeficiency (ESID) registry data

Comorbidities HR: Mean (95% CI)
Results adjusted for the age at CVID diagnosis P value Results adjusted for the age at symptoms onset P value
Bronchiectasis 1.01 (1.00; 1.03) 0.0472 1.03 (1.01; 1.04) 0.0001
Solid tumor 1.01 (0.99; 1.04) 0.2604 1.08 (1.04; 1.11) < 0.0001
Lymphoma 0.96 (0.91; 1.02) 0.1919 0.98 (0.93; 1.04) 0.5713
Splenomegaly 1.00 (0.98; 1.02) 0.9053 1.00 (0.98; 1.02) 0.9611
Chronic lung disease (COPD, asthma) 0.98 (0.96; 1.01) 0.2543 0.99 (0.96; 1.02) 0.4545
Autoimmunity (organ, systemic) 1.00 (0.98; 1.03) 0.9725 1.00 (0.98; 1.03) 0.6958
Enteropathy 1.02 (1.00; 1.04) 0.1206 1.02 (1.00; 1.05) 0.0447
Autoimmune cytopenia 0.97 (0.92; 1.02) 0.1973 0.96 (0.91; 1.01) 0.0892
GLILD 0.90 (0.80; 1.01) 0.0771 0.91 (0.80; 1.02) 0.1045
Granuloma (other than GLILD) 0.98 (0.92; 1.03) 0.3726 0.97 (0.92; 1.03) 0.3362
Lymphoproliferation 0.98 (0.93; 1.03) 0.4132 0.99 (0.94; 1.04) 0.6758