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Table 5 Results of an explorative survival risk factor analysis. Results are obtained with Cox proportional hazards model (N = 2700)

From: The burden of common variable immunodeficiency disorders: a retrospective analysis of the European Society for Immunodeficiency (ESID) registry data

Risk factor HR: Mean (95% CI) P value
Age at diagnosisa 1.04 (1.03; 1.05) <.0001
Age at symptoms onseta 1.04 (1.03, 1.05) <.0001
Sex (female)a 1.14 (0.77; 1.69) 0.515
Age at diagnosisb 1.05 (1.04–1.06) <.0001
Age at symptoms onsetb 1.05 (1.04–1.06) <.0001
Consanguinityc 4.42 (1.66; 11.75) 0.003
Monthly Ig dosec 1.00 (0.99; 1.00) 0.780
Diagnostic delayd 0.99 (0.97–1.01) 0.221
Diagnostic delaye 1.04 (1.02; 1.06) 0.0003
  1. aresuls of a univariable analysis
  2. bresults adjusted for diagnostic delay
  3. cresults stratified for the age at CVID diagnosis and sex
  4. dresults adjusted for the age at CVID diagnosis
  5. eresults adjusted for the age of symptoms onset