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Table 5 Results of an explorative survival risk factor analysis. Results are obtained with Cox proportional hazards model (N = 2700)

From: The burden of common variable immunodeficiency disorders: a retrospective analysis of the European Society for Immunodeficiency (ESID) registry data

Risk factor

HR: Mean (95% CI)

P value

Age at diagnosisa

1.04 (1.03; 1.05)

<.0001

Age at symptoms onseta

1.04 (1.03, 1.05)

<.0001

Sex (female)a

1.14 (0.77; 1.69)

0.515

Age at diagnosisb

1.05 (1.04–1.06)

<.0001

Age at symptoms onsetb

1.05 (1.04–1.06)

<.0001

Consanguinityc

4.42 (1.66; 11.75)

0.003

Monthly Ig dosec

1.00 (0.99; 1.00)

0.780

Diagnostic delayd

0.99 (0.97–1.01)

0.221

Diagnostic delaye

1.04 (1.02; 1.06)

0.0003

  1. aresuls of a univariable analysis
  2. bresults adjusted for diagnostic delay
  3. cresults stratified for the age at CVID diagnosis and sex
  4. dresults adjusted for the age at CVID diagnosis
  5. eresults adjusted for the age of symptoms onset
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172