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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Cost-effectiveness analysis of lumacaftor and ivacaftor combination for the treatment of patients with cystic fibrosis in the United States

Fig. 1

Markov model included five health states: mild (FEV1 > 70%), moderate (FEV1 40–70%), severe (FEV1 < 40%), post-transplant and death and two transition states: pulmonary exacerbation and lung transplant. Transitions to improved states were not allowed for the usual care arm. In some scenarios, transitions to improved states were allowed for the treatment arm

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