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Table 2 Patient Hormone Results

From: Fertility in classical galactosaemia, a study of N-glycan, hormonal and inflammatory gene interactions

 

LH (IU/L)

FSH (IU/L)

Oestradiol (pmol/L)

LH (IU/L)

FSH (IU/L)

Testosterone (nmol/L)(Males only)

Normal reference rangesa

F: 1.8–11.8

F: 3.0–8.1

F: 92–921

1.4–6.5

0–10.9

7.1–31.1

M: 7.6–89.1

M: 2.6–16.7

M: 139–2382

L: 0.6–14.0

L: 1.4–5.5

L: 92–1145

 

CG Females (n = 24)

CG Males (n = 18)

Median

11.57

32.85

460 (n = 9)

< 92 (n = 14)

No data (n = 1)

4.00

2.00

18.80

Mean

14.94

40.89

500.67 (n = 9) < 92 (n = 14)

No data (n = 1)

5.51

8.40

19.98

Range

0.5–40.50

0.5–120

< 92–967

0.5–9.4

0.5–9.3

10–31.6

SD

38.43

12.52

N/A

6.10

2.521.47

5.49

  1. aReference ranges are provided for healthy females and males for LH, FSH and oestradiol for comparison to CG patients, with the females divided into three menstrual stages: Follicular Phase (F), Mid Cycle Phase (M) and Luteal Phase (L). The normal reference ranges were provided from the Investigator site accredited diagnostic laboratory. For CG patients, median, mean and range data are provided with standard deviation (SD)-no menstrual stage data was available. Oestradiol levels less than 92 pmol/L were noted as undetectable according to the limits of the assay. Hormone data was available for 38 of the 54 patients