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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials

Fig. 3

a ASIS scores (total severity/age for every time point) were plotted for each patient over time (years), colour coded to reflect the subgroups from Fig. 1a. b The same data were plotted colour coding patients with seizures in red. c Box and whisker plots demonstrating the greater variability of ASIS scores in the seizure versus non-seizure group. d Density plot of ASIS score variation around zero for seizure, non-seizure groups

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