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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials

Fig. 2

Each of the main clinical subdomains (x-axis) were plotted against total severity score and the coefficient of variation (Spearman’s correlation coefficient) determined (see Additional file 1: Table S1). The dotted line represents the scatterplot’s Friedman’s adaptive smoother. Each patient appears once. Red dots are patients with seizures

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