Fig. 3From: Incidence of tuberous sclerosis and age at first diagnosis: new data and emerging trends from a national, prospective surveillance studyClinical features after comprehensive diagnostic work-up. The majority of patients presented with CNS involvement (cortical dysplasias 51.5% (44/86); subependymal nodules (SEN) 47.7% (41/86) and subependymal giant cell astrocytoma (SEGA) 5,8% (5/86). Followed by cardiac rhabydomyoma in 59.3% (51/86) and hypomelanotic macules in 53.5% (46/86). The other clinical symptoms were heterogeneous. (n: number of patients)Back to article page