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Table 2 Achievement of EAS LDL-C targets at least once during treatment, n (%)

From: Target achievement and cardiovascular event rates with Lomitapide in homozygous Familial Hypercholesterolaemia

Timeframe

Target

< 100 mg/dL (< 2.5 mmol/L)

< 70 mg/dL (< 1.8 mmol/L)

Weeks 0–26a (n = 29)

15 (51%)

8 (28%)

Weeks 0–78a (N = 23)

16 (70%)

9 (39%)

Weeks 0–126b (n = 19

12 (53%)

8 (42%)

Weeks 0–256b (n = 19)

14 (74%)

11 (58%)

  1. EAS European Atherosclerosis Society, LDL-C Low-density lipoprotein cholesterol
  2. aPhase 3 study
  3. bPhase 3 and extension study; values represent number of patients and percentage of enrolled population achieving LDL-C targets at least once in the timeframe
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Orphanet Journal of Rare Diseases

ISSN: 1750-1172