Fig. 2From: Severe hepatopathy and neurological deterioration after start of valproate treatment in a 6-year-old child with mitochondrial tryptophanyl-tRNA synthetase deficiencyBN-PAGE followed by in-gel activity staining. Legend: In-gel activity staining of complex I, II, III, IV and V in liver tissue from the proband compared to a control revealed lower activity of complex I, III and IV in the proband. A catalytically active subcomplex of complex V was seen in the probandBack to article page