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Table 3 Percentage of cases experiencing extremely large variance due to perfect separation on probability scale (confidence interval for difference > 1)

From: Improving the analysis of composite endpoints in rare disease trials

  Standard binary Augmented binary (GLS) Augmented binary (GEE)
N Unadjusted Adjusted Unadjusted Adjusted Unadjusted Adjusted
30 0.00 0.00 10.9 0.00 10.6 0.24
40 0.00 0.00 3.71 0.00 3.81 0.02
50 0.00 0.00 1.11 0.00 1.20 0.00
60 0.00 0.00 0.24 0.00 0.30 0.00
70 0.00 0.00 0.04 0.00 0.08 0.00
80 0.00 0.00 0.00 0.00 0.00 0.00