Table 3 Percentage of cases experiencing extremely large variance due to perfect separation on probability scale (confidence interval for difference > 1)
From: Improving the analysis of composite endpoints in rare disease trials
Standard binary | Augmented binary (GLS) | Augmented binary (GEE) | ||||
|---|---|---|---|---|---|---|
N | Unadjusted | Adjusted | Unadjusted | Adjusted | Unadjusted | Adjusted |
30 | 0.00 | 0.00 | 10.9 | 0.00 | 10.6 | 0.24 |
40 | 0.00 | 0.00 | 3.71 | 0.00 | 3.81 | 0.02 |
50 | 0.00 | 0.00 | 1.11 | 0.00 | 1.20 | 0.00 |
60 | 0.00 | 0.00 | 0.24 | 0.00 | 0.30 | 0.00 |
70 | 0.00 | 0.00 | 0.04 | 0.00 | 0.08 | 0.00 |
80 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 |