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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Beneath the floor: re-analysis of neurodevelopmental outcomes in untreated Hurler syndrome

Fig. 2

Comparison of slopes of decline using Standard Score versus Developmental Quotient (DQ). When plotted against chronological age, Standard Scores reveal the floor effect, with many data points clustered at a score of 50 (left), which affects calculation of slope of decline. By contrast, use of DQ scores eliminates the floor effect and shows many data points lower than 50 (right). With more comprehensive representation of DQs, the slope of decline is more accurately calculated as steeper

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