Fig. 1
From: Beneath the floor: re-analysis of neurodevelopmental outcomes in untreated Hurler syndrome
Developmental Growth Curves for Untreated Hurler Syndrome; Seen between 1983 and 1995. Developmental growth curves depict the patients’ mental ages as compared with their chronological ages at the time of testing. At younger chronological ages, most patients are measuring closer to the curve of normal development. With age, their mental functions depart from the normal developmental trajectory, revealing a plateauing in development and eventual decline, illustrated with a second order polynomial curve fit to the data