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Table 2 Infusion-related signs/symptoms reported by patients at the infusion site during the attacks

From: Safety, effectiveness, and impact on quality of life of self-administration with plasma-derived nanofiltered C1 inhibitor (Berinert®) in patients with hereditary angioedema: the SABHA study

Infusion-related signs/symptoms at the infusion site Absent Mild Moderate Severe
Swelling 123 (66%) 16 (9%) 15 (8%) 33 (18%)
Reddening 122 (65%) 8 (4%) 57 (30%) 0 (0%)
Burning 120 (64%) 47 (25%) 20 (11%) 0 (0%)
Itch 183 (98%) 2 (1%) 2 (1%) 0 (0%)
Feeling of warmth 185 (99%) 2 (1%) 0 (0%) 0 (0%)
Pain 111 (59%) 5 (3%) 56 (30%) 15 (8%)