Table 2 Evolution of the first eye affected and the second eye in five LHON patients during the cyclosporine trial
From: Cyclosporine A does not prevent second-eye involvement in Leber’s hereditary optic neuropathy
First Eye | Second Eye | Inter eye comparaison at exit | ||||||
|---|---|---|---|---|---|---|---|---|
Mean values at baseline | Mean values at exit | P- value | Mean values at baseline | Mean values at exit | P- value | P- values | ||
Visual acuity (logMar) | 0,84 | 1,82 | 0,009* | 0 | 1,50 | 0,001* | 0,40 | |
OCT | Average RNFL thickness (μM) | 142 | 97 | 0,057 | 112 | 122 | 0,57 | 0,30 |
Average GC-PL thickness (μM) | 72,8 | 51,9 | < 0,001* | 80,4 | 56,8 | < 0,001* | 0,18 | |
Visual visual field defect (dB) | −5,2 | −30,0 | < 0,001* | −1,4 | −24,4 | 0,004* | 0,25 | |