Table 4 Evolution of neuropsychological tests between the first and last evaluation
From: Cognitive impairment profile in adult patients with Niemann pick type C disease
Functions | Tests | N | First test mean (SD) | Last test mean (SD) | p |
|---|---|---|---|---|---|
Global cognitive efficiency | MMSE (/30) | 10 | 24.4 (3.4) | 23.5 (3.1) | 0.168 |
Mattis (/140) | 6 | 119 (5.7) | 113.5 (10.3) | 0.115 | |
Executive functions | FAB (/18) | 8 | 13.5 (2.2) | 11.9 (3.1) | 0.140 |
Wisconsin (errors) | 4 | 4 (5) | 5.5 (6.9) | 0.465 | |
Wisconsin (criteria) | 4 | 3.4 (2.4) | 3.8 (2.7) | 0.655 | |
Lexical fluency | 6 | 7.7 (3.1) | 5.3 (1.9) | 0.104 | |
Semantic fluency | 6 | 12.7 (4.4) | 11 (3.7) | 0.673 | |
Attention | Direct verbal span | 5 | 5 (0.7) | 4.4 (0.5) | 0.180 |
Indirect verbal span | 4 | 3 (0.8) | 3.5 (0.6) | 0.157 | |
Direct visual span | 3 | 4.7 (0.6) | 4.7 (0.6) | 1 | |
Indirect visual span | 3 | 4 (1) | 4.3 (0.6) | 0.317 | |
Memory (FCSRT) | Immediate Recall (/16) | 6 | 14 (1.3) | 14.2 (1.2) | 0.564 |
Free recall (/48) | 6 | 20.2 (4.4) | 17.8 (6.7) | 0.136 | |
Total recall (/48) | 6 | 44.8 (4.4) | 43.2 (4.4) | 0.102 | |
Delayed free recall (/16) | 6 | 7 (3.5) | 7.8 (4.1) | 0.595 | |
Delayed total recall (/16) | 6 | 14.3 (2.9) | 14.3 (4.1) | 1 |