Inpatient rehabilitation for adult patients with Marfan syndrome: an observational pilot study

Benninghoven, Dieter; Hamann, Denise; von Kodolitsch, Yskert; Rybczynski, Meike; Lechinger, Julia; Schroeder, Friedrich; Vogler, Marina; Hoberg, Eike

doi:10.1186/s13023-017-0679-0

Orphanet Journal of Rare Diseases

Table 4 Analyses of admission-discharge and admission-follow-up differences in psychological assessments by t-tests for repeated measurements and effect-sizes (Cohen’s d)

From: Inpatient rehabilitation for adult patients with Marfan syndrome: an observational pilot study

assessment scale	admission			discharge			admission to discharge			follow-up			admission to follow-up
assessment scale	m	sd	n	m	sd	n^a	T	p	d	M	sd	n^b	T	p	d
HADS Depression	7.17	4.69	18	5.06	4.21	18	3.43	<.05	0.5	5.0	4.47	16	2.38	<.05	0.5
HADS Anxiety	9.61	5.26	18	6.67	5.42	18	4.17	<.05	0.6	7.0	4.32	16	2.33	<.05	0.5
SCL-90-R Somatization	23.1	7.80	18	20.6	6.36	18	2.14	<.05	0.4	22.3	7.74	16	−.1	.922	0.1
FSS	5.62	.91	18	5.14	1.10	18	2.45	<.05	0.5	4,92	1.51	16	2.33	<.05	0.6
SF-36 physical functioning	59.4	18.1	18	65.6	21.96	18	−1.96	.067	0.3	67.7	23.7	15	−1.61	.129	0.4
SF-36 physical role functioning	41.7	40.2	18	58.3	40.22	18	−1.65	.117	0.4	66,7	40.8	15	−3.29	<.05	0.6
SF-36 bodily pain	46.1	28.8	18	58.4	28.97	17	−2.31	<.05	0.4	51.2	25.7	15	−1.14	.272	0.2
SF-36 general health perception	41.3	15.4	18	47.1	15.52	18	−1.81	.089	0.4	48,6	19.0	14	−1.52	.154	0.4
SF-36 vitality	34.7	13.9	18	51.4	18.13	18	−5.56	<.001	1.0	42.3	21.0	15	−1.79	.096	0.4
SF-36 social role functioning	67.4	33.3	18	74.3	25.18	17	−1.16	.264	0.2	77.7	27.4	14	−1.38	.192	0.3
SF-36 emotional role limitation	59.3	45.1	18	74.5	40.02	17	−1.94	.070	0.4	75.6	38.8	15	−1.42	.178	0.4
SF-36 mental health	59.3	20.7	18	73.8	17.26	18	−4.84	<.001	0.8	66.9	20.5	14	−1.96	.071	0.4
PCS-36	36.3	8.64	18	38.7	9.7	17	−1.22	.240	0.3	40.6	10.4	14	−2.02	.064	0.5
MCS-36	43.4	13.3	18	50.1	10.5	17	−4.13	<.001	0.6	47.8	11.5	14	−1.59	.135	0.4
NHP pain	30.6	33.0	18	25.0	32.65	18	.95	.354	0.2	21,7	31.9	15	.96	.352	0.3
NHP physical mobility	19.4	16.2	18	16.7	19.17	18	.89	.386	0.2	11.7	18.0	15	1.52	.150	0.5
NHP emotional reaction	28.4	26.7	18	14.8	24.10	18	3.42	<.05	0.5	14.1	19.0	15	2.29	<.05	0.6
NHP energy	48.2	40.0	18	29.6	35.95	18	2.15	<.05	0.5	33.3	35.7	15	1.52	.150	0.4
NHP social isolation	8.89	17.1	18	10.0	14.14	18	−.56	.579	−0.1	13.3	19.5	15	−.81	.433	−0.2
NHP sleep	30.0	30.9	18	23.3	28.49	18	2.06	.055	0.2	21.3	29.7	14	.52	.610	0.3

M mean, sd standard deviation, n sample size, T t-value in t-test for repeated measurements, p level of statistical significance, d Cohen’s d, HADS Hospital anxiety and depression Scale, SCL-90-R Symptom Checklist-90-Revised, FSS Fatigue Severity Scale, SF-36 Short Form 36, PCS-36 physical health summary scale of SF-36, MCS-36 mental health summary scale of SF-36, NHP Nottingham Health Profile
^aData from 1 patient of the first cohort is missing
^bData from up to 4 patients is missing

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ISSN: 1750-1172

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