Phenotype prediction for mucopolysaccharidosis type I by in silico analysis

Table 6 Prediction result of PolymiRTS database

SNP ID	miR ID	Conservation	miRSite	Function class
rs733349	hsa-miR-128-3p	1	ggctgCACTGTGc	N
	hsa-miR-148a-3p	1	ggcTGCACTGtgc	N
	hsa-miR-148b-3p	1	ggcTGCACTGtgc	N
	hsa-miR-152-3p	1	ggcTGCACTGtgc	N
	hsa-miR-216a-3p	1	ggctgCACTGTGc	N
	hsa-miR-3681-3p	1	ggctgCACTGTGc	N
	hsa-miR-3944-5p	1	gGCTGCACtgtgc	N
	hsa-miR-7156-3p	1	GGCTGCActgtgc	N
	hsa-miR-4436b-3p	1	ggCTGCCCTgtgc	C
	hsa-miR-4632–5p	1	ggCTGCCCTgtgc	C
	hsa-miR-6735-5p	1	ggCTGCCCTgtgc	C
	hsa-miR-6879-5p	1	ggCTGCCCTgtgc	C
	hsa-miR-7843-5p	1	ggCTGCCCTgtgc	C

Conservation: Occurrence of the miRNA site in other vertebrate genomes in addition to the query genome. By clicking the hyperlink, the users can examine the genomes in which this miRNA target site occurs. miRSite: Bases complementary to the seed region are in capital letters. Explanation of the function class is listed as followed. D: The derived allele disrupts a conserved miRNA site (ancestral allele with support > = 2). N: The derived allele disrupts a nonconserved miRNA site (ancestral allele with support <2). C: The derived allele creates a new miRNA site. O: The ancestral allele cannot be determined

ISSN: 1750-1172