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Table 2 Clinical characteristics of chILD patients at initial presentation to reporting centre

From: Childhood interstitial lung diseases in immunocompetent children in Australia and New Zealand: a decade’s experience

  N (%) All cases Diagnosis < 2 years Diagnosis ≥ 2 years
   No. reported
(Max 107)
N (%) No. reported
(Max 66)a
N (%) No. reported
(Max 40)a
Sex: male/female 59/45
(57/43)
104 40/26
(61/39)
66 19/18
(51/49)
37
Age at Diagnosis (years) 0.01–18.00   0.01–1.92   2.00–18.00  
Median (range)    0.50   8.20  
Ethnic Origin   57   27   30
 Caucasian 41 (72.0)   21 (77.8)   20 (66.8)  
 Aboriginal 2 (3.5)   2 (7.4)   0  
 Maori 6 (10.5)   2 (7.4)   4 (13.3)  
 Pacific Islander 2 (3.5)   0   2 (6.6)  
 Other 6 (10.5)   2 (7.4)   4 (13.3)  
Parental Consanguinity 3 (5.8) 51 0 26 3 (12.0) 25
Family History
 Affected siblings 7 (8.1) 86 6 (12.0) 50 1 (2.7) 36
 Other family members affected 3 (4.0) 75 3 (7.5) 40 0 35
Symptoms
 Cough 51 (56.0) 91 24 (47.0) 51 26 (66.7) 39
 Tachypnoea 76 (76.7) 99 54 (91.5) 59 22 (55.0) 40
 Failure to thrive 35 (40.2) 87 26 (53.1) 49 9 (23.7) 38
 Fever 12 (13.8) 87 7 (14.6) 48 5 (12.8) 39
 Exertion dyspnoea 42 (56.0) 75 16 (41.0) 39 26 (72.2) 36
 Dyspnoea at rest 43 (50.0) 86 26 (53.1) 49 17 (45.9) 37
Physical Findings
 Cyanosis 22 (22.7) 97 11 (19.3) 57 11 (28.2) 39
 Clubbing 13 (14.3) 91 3 (5.9) 51 10 (25.6) 39
 Crackles 56 (58.3) 96 29 (51.8) 56 26 (66.7) 39
 Wheeze 20 (22.7) 88 12 (23.5) 51 8 (21.6) 37
Birth History
Mode of delivery
  Spontaneous vaginal birth 61 (77.2) 79 40 (74.1) 54 20 (83.3) 24
Gestation
   < 37 weeks 18 (21.4) 84 15 (25.4) 59 3 (12.0) 25
   ≥ 37 weeks 66 (78.6) 84 44 (74.6) 59 22 (88.0) 25
Respiratory distress at birth 31 (41.3) 75 26 (57.8) 45 4 (13.8) 29
  Intubation at birth 20 (24.7) 81 18 (38.3) 47 2 (6.1) 33
  Surfactant at birth 7 (9.2) 76 7 (15.9) 44 0 32
  1. a Age at diagnosis was not documented for 1 subject