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Table 6 Information for patients

From: Management of everolimus-associated adverse events in patients with tuberous sclerosis complex: a practical guide

Infection

• Patients should be advised that they may be more susceptible to infections during treatment with everolimus, and to be aware of and to promptly report to a healthcare professional any signs and symptoms of infection, including a raised temperature

Stomatitis

• Brush teeth regularly and gently with a soft toothbrush

• Use a mild toothpaste (e.g. children’s toothpaste)

• Rise frequently with a bland mouthwash, such as water or a salt mouthwash (e.g. half a teaspoon of salt in a cup of warm water)

• Avoid mouthwashes containing alcohol

• Avoid hot food (in temperature and/spiciness) or crunchy food

Non-infectious pneumonitis

• Patients should be advised to promptly report any new or worsening respiratory symptoms

Rash

• Use a mild, unperfumed soap

• Wear loose convertible clothes

• When washing and drying the body, pat dry instead of rubbing with a towel

• Moisturise frequently

• Take short, lukewarm showers

• Use sunscreen (at least SPF 15)