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Table 2 Disease and Treatment Characteristics by Time since Diagnosis and Cardiac Involvement

From: The burden of amyloid light chain amyloidosis on health-related quality of life

  Time since diagnosis   Cardiac involvement  
  <12 months n = 52 ≥12 months n = 289   No n = 163 Yes n = 178  
  n % n % P value n % n % P value
No. organs involved      0.047      <0.001
 One 20 38.5 75 26.0   71 43.6 24 13.5  
 Two 16 30.8 73 25.3   42 25.8 47 26.4  
 Three or more 16 30.8 141 48.8   50 30.7 107 60.1  
No. treatment series received           0.889
 None 8 15.4 12 4.2 <0.001 12 7.4 8 4.5  
 One 16 30.8 54 18.7   32 19.6 38 21.3  
 Two 5 9.6 71 24.6   34 20.9 42 23.6  
 Three 4 7.7 57 19.7   29 17.8 32 18.0  
 Four 5 9.6 20 6.9   12 7.4 13 7.3  
 Five or more 14 26.9 75 26.0   44 27.0 45 25.3  
Ever underwent stem cell transplantation (% yes) 5 9.8 175 60.6 <0.001 89 54.6 91 51.4 0.556
Most recent hematologic response statusa      <0.008      0.135
 No response to treatment 5 11.6 15 5.4   9 6.0 11 6.5  
 Partial hematologic response or partial remission 19 44.2 107 38.5   62 41.1 64 37.7  
 Complete hematologic response or complete remission 10 23.3 130 46.8   58 38.4 82 48.2  
 I do not know 9 20.9 26 9.4   22 14.6 13 7.7  
  1. aFrequencies and percentages are based on the 321 patients who received at least one treatment series