|
CNS
|
Tone regulation
|
Floppy infant
|
+
|
++
| | | |
|
Hypotonia (mainly truncal)
|
+
|
++
|
++
|
++
|
++
|
|
Poor head control
|
+
|
+
|
+
|
+
|
+
|
|
Hypertonia (mainly limbs)
|
+
|
+
|
+
|
+
|
+
|
|
Movement disorders
|
Dyskinesia (eg hyperkinesia, chorea, athetosis)
|
±
|
+
|
+
|
+
|
+
|
|
Dystonia
|
-
|
++
|
++
|
++
|
++
|
|
Oculogyric crisis
|
±
|
++
|
++
|
++
|
++
|
|
Hypokinesia and/ or bradykinesia
|
±
|
++
|
++
|
++
|
++
|
|
Myoclonus
|
±
|
±
|
±
|
±
|
±
|
|
Tremor
|
±
|
±
|
±
|
±
|
±
|
|
Developmental Delay
|
Delayed motor development
|
±
|
++
|
++
|
++
|
++
|
|
Delayed cognitive development
| |
±
|
+
|
+
|
+
|
|
Delayed speech development
| |
±
|
+
|
+
|
+
|
|
Behavioural Problems
|
Irritability
|
++
|
++
|
+
|
+
|
+
|
|
Autistic features
| | |
±
|
±
|
±
|
|
Dysphoria/ Mood problems
|
±
|
±
|
±
|
±
|
±
|
|
Excessive crying
|
+
|
++
|
+
|
-
|
-
|
|
Sleeping Problems
|
Insomnia and or hypersomnia
| |
+
|
+
|
+
|
+
|
|
Other
|
Epileptic seizures
|
-
|
±
|
±
|
±
|
±
|
|
Fatiguability
|
±
|
±
|
±
|
±
|
±
|
|
Diurnal fluctuation
| |
±
|
±
|
±
|
±
|
|
Dysarthria
| | |
±
|
±
|
±
|
|
Poor eye fixation
| |
+
|
+
|
+
|
+
|
|
Increased startle
|
±
|
±
|
±
|
±
|
±
|
|
ANS
|
Eyes
|
Ptosis
|
+
|
+
|
+
|
+
|
+
|
|
Miosis
|
±
|
±
|
±
|
±
|
±
|
|
Upper respiratory tract
|
Nasal congestion
|
-
|
+
|
+
|
±
|
±
|
|
Excessive drooling
|
-
|
+
|
+
|
±
|
±
|
|
Stridor
|
±
|
±
|
±
|
±
|
±
|
|
Skin
|
Excessive sweating
|
-
|
+
|
+
|
+
|
+
|
|
Homeostasis
|
Temperature instability
|
+
|
+
|
+
|
+
|
+
|
|
Cardiovascular
|
(Orthostatic) Hypotension
|
-
|
-
|
±
|
+
|
+
|
|
Bradycardia
|
±
|
±
|
±
|
±
|
±
|
|
Heart rhytm abnormalities
|
±
|
±
|
±
|
±
| |
|
Gastrointestinal
|
Diarrhea
|
±
|
+
|
+
|
+
|
±
|
|
Obstipation
|
±
|
+
|
+
|
+
|
±
|
|
Metabolic/ endocrine
|
Hypoglycemia
|
±
|
±
|
±
|
-
|
-
|
|
Hyperprolactinemia
|
±
|
±
|
±
|
±
|
±
|
|
General
|
Feeding/ Swallowing Problems
|
+
|
+
|
+
|
+
|
+
|
|
Gastrointestinal reflux
|
+
|
+
|
+
|
±
|
±
|
|
Gastrointestinal problems unspecified
|
+
|
++
|
+
|
+
|
+
|
|
Failure to thrive
|
±
|
+
|
+
|
+
| |
|
Contractures
|
-
|
-
|
-
|
±
|
±
|
|
Small hand and feet
|
±
|
±
|
±
|
±
|
±
|
