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Table 5 Health related quality of life

From: Ataxia, dystonia and myoclonus in adult patients with Niemann-Pick type C

RAND-36 domains

Study population, mean (SD)

General population, mean (SD)

p-value*

Physical

43.1 (40.9)

81.9 (23.2)

p = 0.007

Social

73.4 (33.0)

86.9 (20.5)

p = 0.248

Role limitations (physical)

43.8 (37.5)

79.4 (35.5)

p = 0.008

Role limitations (emotional)

70.8 (45.2)

84.1 (32.3)

p = 0.406

Mental health

84.0 (10.5)

76.8 (18.4)

p = 0.055

Vitality

55.0 (16.5)

67.4 (19.9)

p = 0.035

Pain

93.1 (19.5)

79.5 (25.6)

p = 0.051

General health

35.0 (17.9)

72.7 (22.7)

p < 0.001

Health change

50.0 (29.9)

52.4 (19.4)

p = 0.821

  1. SD standard deviation
  2. *Independent samples t-test for equality of means, significance level p < 0,05