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Table 2 Baseline and follow up PSG data in children with suspected ROHHAD

From: ROHHAD syndrome and evolution of sleep disordered breathing

Baseline PSG Follow-up PSG
Pt BMI (kg/m2) Age (years) PSG Diagnosis SaO2 Min (%) Co2 range (mmHg) Treatment • Time interval (years)
• N of PSG
BMI (kg/m2) PSG diagnosis CO2 range (mmHg) Treatment
1 35.7 4.7 Mild OSA 79 41–47 Weight loss • 1y 4 m 43.5 Severe OSA and NH 50–54 • Bi-Level PAP
• OAHI 3/h
• CAI 0/h
• 5 • OAHI 12/h
• CAI 0/h
  • Suppl. Oxygen (day)
2 28.5 9.0 Mild OSA 82 41–49 Weight loss • 2y 5 m 36.4 Moderate OSA and NH 35–52 Bi-Level PAP
• OAHI 4/h
• CAI 0/h
• 3 • OAHI 9/h
• CAI 0/h
3 26.5 10.1 Severe OSA 83 29–38 •Adenotonsillectomy
• Weight loss
• 6 m 26.6 Severe OSA and NH 40–53 • Bi-Level PAP
• OAHI 49/h
• CAI 0/h
  • 1 • OAHI 142/h
• CAI 2.9/h
• Oxygen (day and night)
4 40.7 8.3 NH 90 47–60 Bi-Level PAP • 8 m 40.4 No change #32–39 Maintained on Bi-Level PAP
• OAHI 0/h
• CAI 0/h
• 1 • OAHI 0/h
• CAI 0/h
5 40.8 5.3 Severe OSA and NH 67 50–86 Bi-Level PAP - - • NOT PERFORMED - -
• OAHI 11/h
• CAI 0/h
• Pt deceased
6 39.9 10.0 Mild OSA 81 38–44 Weight loss • 4y 8 m 47.6 Severe OSA and NH Peak 51 Bi-Level PAP
• OAHI 4/h
• CAI 0/h
• 8 • OAHI 18/h
• CAI 0/h
  1. Time Interval describes the time between the first and follow-up PSG in the table; Number of PSG refers to the total number of PSG that were performed between the first PSG and the follow-up PSG in the table; # - patient number 4 was not hypercapnic on follow-up PSG as this was undertaken on Bi-Level PAP
  2. Abbreviations: OSA obstructive sleep apnea, NH nocturnal hypoventilation, OAHI obstructive apnea hypopnea index, CAI central apnea index, AT adenotonsillectomy