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Table 1 Changes in FSFI scores and laboratory parameters after 12-month combination therapy in Female patients

From: Improvement of sexual function in POEMS syndrome after combination therapy of Lenalidomide and dexamethasone

 

Baseline (N = 12)

End of study (N = 10)

95 % confidence interval of the diff (N = 10)

P value

Lower

Upper

FSFI Domains Desire

5.6 ± 0.9

5.5 ± 1.0

−0.9

0.6

0.468

Arousal

2.6 ± 1.9

4.6 ± 1.8

0.6

4.0

0.002*

Lubrication

2.3 ± 1.9

3.3 ± 2.0

−0.8

3.3

0.084

Orgasm

2.3 ± 1.9

3.5 ± 2.1

−0.6

3.4

0.050*

Satisfaction

2.4 ± 1.2

3.2 ± 2.0

−0.6

2.1

0.112

Pain

2.0 ± 1.6

3.8 ± 2.4

−0.7

4.8

0.046*

Total FSFI score

17.1 ± 7.2

23.7 ± 7.2

1.5

13.6

0.003*

FSH (IU/L)

12.38 ± 13.47

33.20 ± 28.75

4.45

61.95

0.067

LH (IU/L)

8.05 ± 9.09

17.26 ± 18.81

−1.55

36.07

0.017*

E2 (pg/mL)

81.92 ± 62.62

59.50 ± 92.79

−93.99

113.69

0.771

VEGF (pg/mL)

6190.5 ± 3979.3

1468.2 ± 1495.4

908.7

8871.7

0.004*

  1. SD standard deviation