Invasive meningococcal disease in three siblings with hereditary deficiency of the 8th component of complement: evidence for the importance of an early diagnosis

Table 2 Evaluation of complement deficiency by haemolytic assay in serum from the 3 patients after adding serum with the deficiency (def) of a single complement component

Patient’s serum + :	Patient 1	Patient 2	Patient 3
Patient’s serum + :	(% of lysis)	(% of lysis)	(% of lysis)
C5 def serum	99	95	90
C6 def serum	94	95	79
C7 def serum	100	100	96
C8 alpha-gamma def serum	95	87	88
C8 beta def serum	0	0	0
C8 beta def serum + human C8	99	100	94
C9 def serum	100	100	100

ISSN: 1750-1172