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Table 1 Description of the population

From: High unacylated ghrelin levels support the concept of anorexia in infants with prader-willi syndrome

  PWS (n = 37) Controls (n = 100) P valuea
At birth
 Gestational age (weeks) 37.5 (36.0;39.0) 39.5 (39.0;39.5) 0.008
 Caesarean delivery (%) 67 % 28 % <0.0001
 Birth length-z-score −0.85 (−1.08;–0.60) −0.29 (−0.56;–0.06) 0.010
 Birth weight-z-score −1.65 (−1.90;–1.31) −0.26 (−0.50;–0.02) <0.0001
 Breast feeding (%) 11 %b 66 % <0.0001
 Duration of breast feeding (days) 92 (45;151) 135 (99;167) NS
At inclusion
 Age (years) 1.8 (1.4;2.3) 2.0 (1.7;2.2) NS
 Sex ratio (% male) 57 % 49 % NS
 Height-z-score −0.84 (−1.23;–0.48) 0.53 (0.25;0.80) <0.0001
 Weight-z-score −1.06 (−1.49;–0.64) 0.06 (−0.20;0.35) <0.0001
 BMI-z-score −0.86 (−1.31;–0.32) −0.40 (−0.70;–0.10) NS
 GH treatment (%) 68 % NA NA
 Age at start of GH treatment (months) 13.0 (11.0;15.5) NA NA
 GH dose (mcg/kg/d) 0.029 (0.027;0.031) NA NA
 IGF-I (ng/ml) 98 (61;135) NA NA
 Insulin (pg/ml) 167 (141;194) 178 (160;196) NS
PWS features
 Age at genetic diagnosis (months) 1.0 (0.5;2.5)  
 Type of genetic diagnosis (%)
  Deletion 24 %
  Maternal disomy 51 %
  Translocation 3 %
  Imprinting defect 11 %
  Abnormal methylation profile 11 %
Nutritional phase at inclusion
 1a [%−age (months(range))] 43 %−4 (2;23)
 1b [%−age (months(range))] 20 %−29 (11;45)
 2a [%−age (months(range))] 23 %−38 (21;46)
 2b [%−age (months(range))] 14 %−34 (26;37)
  1. Table 1 gives % or Hodges-Lehmann’s medians and their 95 % confidence interval
  2. Abbreviations: NA Not applicable, NS Not Significant
  3. aDifferences between PWS vs. controls were tested with Mann–Whitney or Chi-square tests
  4. bMother’s milk was given without complete breast feeding to PWS infants