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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Alternative laronidase dose regimen for patients with mucopolysaccharidosis I: a multinational, retrospective, chart review case series

Fig. 1

Changes in organomegaly. Organomegaly at time of diagnosis (T1), initiation of laronidase every other week dosing following weekly laronidase dosing regimen (T2), and follow-up assessment (T3). In 6 patients (aqua) there was no organomegaly at any time point. In 6 patients (red), organomegaly present at T1 was absent at T2 and T3. In six of the remaining patients (blue, and green), organomegaly was improved/absent at T3 compared to T1, and in one patient (yellow) organomegaly was not changed at T2 or T3 compared to T1

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