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Table 6 Behavioural Characteristics in 101 PTHS Individuals

From: Phenotype and natural history in 101 individuals with Pitt-Hopkins syndrome through an internet questionnaire system

Behaviour

Percent

Unusual behaviour during feeding

40.4 %

Sleep problems

No longer periods of sleep/frequently awake at night

4.4 %

Other sleep problems

4.4 %

Problems falling asleep

Previously

12.1 %

Currently

17.6 %

Problems sleeping the whole night through

Previously

13.6 %

Currently

33.0 %

Night terrors

Previously

6.6 %

Currently

5.5 %

Hand biting

Previously

11.4 %

Currently

58.0 %

Mean age of start

4.2 years (range 0–23 years)

Teeth grinding

Previously

28.9 %

Currently

46.7 %

Mean age of start

2.8 years (range 0–12 years)

Clapping/flashing/hand washing

Previously

9.0 %

Currently

80.9 %

Mean age of start

1.7 years (range 0–15 years)

Repetitive movements

Previously

4.4 %

Currently

66.7 %

Mean age of start

3.3 years (range 0.2–12 years)