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Table 3 Neuropsychological functioning. Test scores are expressed as mean, (SD). Percentages of impairment (% impaired) are related to available cut-off scores of normality (≥95 % of the tolerance limit of the normal population distribution); statistically significant differences between patients and healthy controls are shown in bold

From: Disease awareness in myotonic dystrophy type 1: an observational cross-sectional study

 

DM1 patients (n = 65)

Controls (n = 26)

 

mean corrected scores

% impaired

mean corrected scores

p-value

RAVLT IR

42 (7.2)

5.8

46.8 (8.4)

.013

RAVLT DR

9.1 (1.8)

1.9

9.8 (2.5)

.370

Rey Osterrieth Figure (ROCF) Copy

27.5 (6.5)

46.9

32 (6.5)

.007

Rey Osterrieth Figure (ROCF) IR

13.8 (6.0)

32.7

19.8 (6.6)

< .001

Rey Osterrieth Figure (ROCF) DR

13.2 (6.7)

36.7

19.7 (6.4)

< .001

Digit Span

5.1 (1.1)

24

6.2 (1.2)

.002

Corsi’s Block Test (CBT)

4 (0.8)

43.1

5 (0.8)

< .001

Trail Making Test A (TMT A)

55.5 (34.9)

21.3

41 (14.3)

.003

Trail making Test B (TMT B)

130.5 (60)

17.4

108.3 (47.2)

.072

FAS (phonemic fluency)

28.4 (9.8)

25.5

44.7 (9.0)

< .001

FAB

15 (1.4)

25

16.3 (0.6)

< .001

STROOP Time Interference

32.8 (24.8)

32.7

18.9 (6.4)

< .001

STROOP Error Interference

3.2 (4.4)

36.7

1 (0.9)

.001

PM47

30.8 (36.4)

18.9

30.6 (2.3)

< .001

WCST Categories (Cat)

3.8 (1.9)

43.4

5.6 (0.8)

< .001

WCST Perseverative Errors (pe)

5.5 (4.4)

47.2

1.9 (1.2)

< .001