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Table 3 Quality assessment of the studies on paediatric MS (References [2832, 3437, 6062]) and on CJD (References [3841, 43, 44, 63])

From: Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions

Studies on paediatric MS  
AAN scale Oxford quality scale for RCTs References
Class II 2 points [28]
Class III n/a [29, 30, 37, 60, 62]
Class IV n/a [31, 32, 3436, 61]
Studies on CJD  
AAN scale Oxford quality scale for RCTs References
Class I 5 points [39, 41]
Class I 4 points [38]
Class III n/a [40, 43, 44, 63]