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Table 1 Number of selected studies on paediatric MS and CJD meeting specific criteria

From: Systematic reviews in paediatric multiple sclerosis and Creutzfeldt-Jakob disease exemplify shortcomings in methods used to evaluate therapies in rare conditions

 

RCT

Clinical endpoints

Prospective analysis

Sample size calculation

Adjustments for multiple testing

Confounding addressed

Industry sponsored

Paediatric MS (n = 12)

1

12

6

1

1

2

3

CJD (n = 7)

3

7

5

4

0

4

1

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172