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Table 3 Baseline results in patients vs. controls

From: Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency

Baseline Measurements

      
 

Mean (SD)

 

P value (T-test)

aMean % Reference (SD)

 

P value (t-test)

Spirometry

Patients n = 5

Controls n = 82

 

Patients n = 5

Controls n = 82

 

FEV1 (L)

2.2 (1.0)

1.85 (0.7)

0.354

86.0 (8.2)

90.8 (22.4)

0.636

FVC (L)

2.5 (1.2)

2.28 (0.9)

0.576

89.8 (11.8)

100.7 (17.6)

0.178

FEV1/FVC (%)

86.8 (3.4)

82.0 (9.9)

0.282

   

PEF (L/sec)

6.2 (3.6)

4.0 (1.6)

0.007

104.8 (25.5)

95.1(25.8)

0.418

Impulse oscillometry

Patients n = 10

Controls n = 82

 

Patients n = 10

Controls n = 82

 

R5 (cmH20/L/sec)

8.4 (3.3)

7.8 (2.3)

0.488

122.3 (33.3)

103.4 (24.7)

0.032

R10 (cmH20/L/sec)

6.9 (2.5)

6.4 (1.7)

0.451

112.3 (33.9)

95.9 (22.4)

0.044

R20 (cmH20/L/sec)

5.7 (1.9)

5.4 (1.3)

0.592

98.0 (27.0)

93.8 (22.5)

0.592

R5-R20 (%)Δ

30.6 (9.4)

29.6 (11.0)

0.780

   

X5 (cmH20/L/sec)

−3.6 (1.8)

−3.0 (1.3)

0.231

182 (78.7)

118.7 (50)

0.001

AX (cmH20/L)

27.5 (21.6)

22.4 (14.6)

0.323

   

Fres Hz

22.2 (6.3)

20.5 (4.4)

0.280

   

X5ref-X5 (cmH20/L/sec)

1.3 (1.2)

0.35 (1.3)

0.041

   
  1. aNormal cut-off: Spirometry >80 % Reference; IOS: R5, R10, R20, <140 % Ref, X5ref-X5 < 1.5 cm H20/L/sec, ΔR5-R20 < 35 %