Impulse oscillometry identifies peripheral airway dysfunction in children with adenosine deaminase deficiency

Table 1 Patient characteristics and pulmonary imaging and function testing

UPN	Age (years)	Gender	Ethnicity^a	Treatment^b	CT	Spirometry	IOS
1-ADA26	3	F	C	1	ND	-	+
2-ADA41	5	F	C	2	ND	-	+
3-ADA14	8	F	C	2	Normal	+	+
4-ADA16	9	M	H	1	dGGO, MA, B	-	+
5-ADA18	10	F	A	2	ND	+	+
6-ADA5	12	M	AA	1	MA	+	+
7-ADA46	14	F	C	2	dGGO, PC, MA, N	-	+
8-ADA17	16	F	AA	2	MA	-	+
9-ADA3	17	M	C	2	dGGO, PC	+	+
10-ADA47	18	M	AA	2	ND	+	+

^aC = Caucasian, H = Hispanic, A = Asian, AA = African American
^b1 = Gene Therapy; 2 = ADA conjugated with polyethylene glycol (PEG-ADA)
CT findings: ND CT not performed, dGGO diffuse ground glass opacities, PC parenchymal Cysts, MA Mosaic attenuation, B Bronchiectasis, N Nodules
+ Indicates successful completion of Spirometry and/or IOS

ISSN: 1750-1172