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Table 2 Demographic, haemodynamic and biochemical data

From: Diffuse left ventricular interstitial fibrosis is associated with sub-clinical myocardial dysfunction in Alström Syndrome: an observational study

 

Controls

ALMS

Number n

26

26

Age years

27 ± 6

27 ± 9

Male n (%)

17 (65 %)

17 (65 %)

Height (m)

1.74 ± 0.09

1.61 ± 0.09**

Weight (Kg)

76 ± 16

77 ± 16

Body Mass Index

25 ± 4

30 ± 5**

Haemoglobin (g/dL)

14.3 ± 1.2

14.0 ± 2.2

eGFR (ml/min/1.73 m2)

87 ± 8

73 ± 25*

Renin (pg/ml) a

-

41 (18–153)

Aldosterone (pg/ml) a

-

97 (67–220)

NT-pro BNP (ng/L) a

38 (4–75)

37 (17–89)

Cholesterol (mmol/L)

4.6 (0.8)

5.1 ± 1.3

Triglycerides (mmol/L) a

1.0 (0.6–1.4)

2.5 (1.5–4.1)**

High Density Lipoprotein (mmol/L)

1.4 (0.3)

0.9 ± 0.3**

Glucose (mmol/L) a

4.7 (4.2–5.0)

6.1 (4.6–15.0)*

HbA1c (%)

-

7.9 ± 2.7

Insulin (pmol/L) a

-

858 (239–1760)

C-peptide:Glucose ratio (ng/ml:mg/dl) a

-

4.2 (2.2–6.2)

ACR (mg/mmol) a

0.1 (0.05–0.2)

1.5 (0.25–34)

Urate (mmol/L)

286 ± 67

409 ± 111*

24 h daytime SBP (mmHg)

119 ± 9

130 ± 14*

24 h daytime DBP (mmHg)

72 ± 7

77 ± 9*

  1. ACR albumin/creatinine ratio, ALMS Alström Syndrome, DBP diastolic blood pressure, eGFR Estimated glomerular filtration rate, HBA 1c glycated haemoglobin, NT-pro BNP N-terminal pro B natriuretic peptide, SBP systolic blood pressure
  2. Value ± standard deviation, amedian (inter-quartile range), p = * < 0.05, p = ** <0.01