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Table 2 Demographic, haemodynamic and biochemical data

From: Diffuse left ventricular interstitial fibrosis is associated with sub-clinical myocardial dysfunction in Alström Syndrome: an observational study

  Controls ALMS
Number n 26 26
Age years 27 ± 6 27 ± 9
Male n (%) 17 (65 %) 17 (65 %)
Height (m) 1.74 ± 0.09 1.61 ± 0.09**
Weight (Kg) 76 ± 16 77 ± 16
Body Mass Index 25 ± 4 30 ± 5**
Haemoglobin (g/dL) 14.3 ± 1.2 14.0 ± 2.2
eGFR (ml/min/1.73 m2) 87 ± 8 73 ± 25*
Renin (pg/ml) a - 41 (18–153)
Aldosterone (pg/ml) a - 97 (67–220)
NT-pro BNP (ng/L) a 38 (4–75) 37 (17–89)
Cholesterol (mmol/L) 4.6 (0.8) 5.1 ± 1.3
Triglycerides (mmol/L) a 1.0 (0.6–1.4) 2.5 (1.5–4.1)**
High Density Lipoprotein (mmol/L) 1.4 (0.3) 0.9 ± 0.3**
Glucose (mmol/L) a 4.7 (4.2–5.0) 6.1 (4.6–15.0)*
HbA1c (%) - 7.9 ± 2.7
Insulin (pmol/L) a - 858 (239–1760)
C-peptide:Glucose ratio (ng/ml:mg/dl) a - 4.2 (2.2–6.2)
ACR (mg/mmol) a 0.1 (0.05–0.2) 1.5 (0.25–34)
Urate (mmol/L) 286 ± 67 409 ± 111*
24 h daytime SBP (mmHg) 119 ± 9 130 ± 14*
24 h daytime DBP (mmHg) 72 ± 7 77 ± 9*
  1. ACR albumin/creatinine ratio, ALMS Alström Syndrome, DBP diastolic blood pressure, eGFR Estimated glomerular filtration rate, HBA 1c glycated haemoglobin, NT-pro BNP N-terminal pro B natriuretic peptide, SBP systolic blood pressure
  2. Value ± standard deviation, amedian (inter-quartile range), p = * < 0.05, p = ** <0.01