Table 2 Bivariate and multivariate analyses of D0 biological parameters associated with %DRBC change under HU
From: Biological parameters predictive of percent dense red blood cell decrease under hydroxyurea
Bivariate analysis | Multivariate analysis* | |||
|---|---|---|---|---|
Parameter | r | p value | β-coefficient | p value |
%DRBCs | −0.863 | <0.0001 | −0.885 | <0.0001 |
WBCs (G/L) | −0.257 | 0.068 | – | – |
MCV (fl) | −0.018 | 0.902 | – | – |
MCHC (g/dL) | −0.485 | 0.0004 | 0.668 | 0.404 |
MCH (pg) | −0.140 | 0.332 | – | – |
Hb (g/dL) | 0.097 | 0.501 | – | – |
%HbF | 0.099 | 0.484 | – | – |
Reticulocytes (G/L) | −0.437 | 0.002 | −0.004 | 0.703 |
Platelets (G/L) | 0.200 | 0.159 | – | – |
Total bilirubin (μmol/L) | −0.426 | 0.002 | 0.034 | 0.285 |
ALT (IU/L) | −0.144 | 0.310 | – | – |
AST (IU/L) | −0.419 | 0.002 | −0.023 | 0.285 |
LDH (IU/L) | −0.324 | 0.020 | −0.001 | 0.801 |