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Figure 3 | Orphanet Journal of Rare Diseases

Figure 3

From: Immunogenicity of idursulfase and clinical outcomes in very young patients (16 months to 7.5 years) with mucopolysaccharidosis II (Hunter syndrome)

Figure 3

The ILS over time by PAb status and genotype group. A) ILS over time by PAb status at the landmark point. Week 53, PAb+ vs PAb−, p = 0.025. B) ILS over time by genotype group. Week 53, FS/SSM vs MS, p = 0.049. CD/LR, complete deletion/large rearrangement; FS/SSM, frameshift/splice site mutation; ILS, index of liver size; MS, missense mutation; PAb+, persistently antibody positive; PAb−, persistently antibody negative.

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172